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Generation of Hutat2:Fc Knockin Primary Human Monocytes Using CRISPR/Cas9
The ability of monocytes to travel through the bloodstream, traverse tissue barriers, and aggregate at disease sites endows these cells with the attractive potential to carry therapeutic genes into the nervous system. However, gene editing in primary human monocytes has long been a challenge. Here,...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992333/ https://www.ncbi.nlm.nih.gov/pubmed/29858049 http://dx.doi.org/10.1016/j.omtn.2018.01.012 |