Generation of Hutat2:Fc Knockin Primary Human Monocytes Using CRISPR/Cas9

The ability of monocytes to travel through the bloodstream, traverse tissue barriers, and aggregate at disease sites endows these cells with the attractive potential to carry therapeutic genes into the nervous system. However, gene editing in primary human monocytes has long been a challenge. Here,...

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Detalles Bibliográficos
Autores principales: Wang, Bowen, Zuo, Jiahui, Kang, Wenzhen, Wei, Qianqi, Li, Jianhui, Wang, Chunfu, Liu, Zhihui, Lu, Yuanan, Zhuang, Yan, Dang, Bianli, Liu, Qing, Kang, Wen, Sun, Yongtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992333/
https://www.ncbi.nlm.nih.gov/pubmed/29858049
http://dx.doi.org/10.1016/j.omtn.2018.01.012

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