Saponins as Natural Adjuvant for Antisense Morpholino Oligonucleotides Delivery In Vitro and in mdx Mice

Antisense oligonucleotide (AON) therapy for Duchenne muscular dystrophy has drawn great attention in preclinical and clinical trials, but its therapeutic applications are still limited due to inefficient delivery. In this study, we investigated a few saponins for their potential to improve delivery...

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Detalles Bibliográficos
Autores principales: Wang, Mingxing, Wu, Bo, Shah, Sapana N., Lu, Peijuan, Lu, Qilong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992344/
https://www.ncbi.nlm.nih.gov/pubmed/29858054
http://dx.doi.org/10.1016/j.omtn.2018.02.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992344/
https://www.ncbi.nlm.nih.gov/pubmed/29858054
http://dx.doi.org/10.1016/j.omtn.2018.02.004

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