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Cdk5 Inhibitory Peptide Prevents Loss of Dopaminergic Neurons and Alleviates Behavioral Changes in an MPTP Induced Parkinson’s Disease Mouse Model

Parkinson’s disease (PD) is one of the most affected neurodegenerative diseases in the world. Deregulation of cyclin-dependent kinase 5 (Cdk5) is believed to play an important role in neurodegenerative diseases including PD. p25 is a cleavage peptide of p35, a physiologic activator of Cdk5. p25 comb...

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Detalles Bibliográficos
Autores principales:	He, Rongni, Huang, Wei, Huang, Yaowei, Xu, Miaojing, Song, Pingping, Huang, Yinwei, Xie, Huifang, Hu, Yafang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992349/ https://www.ncbi.nlm.nih.gov/pubmed/29910724 http://dx.doi.org/10.3389/fnagi.2018.00162

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