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Mechanisms and Approaches for Overcoming Enzalutamide Resistance in Prostate Cancer

Enzalutamide, a second-generation small-molecule inhibitor of the androgen receptor (AR), has been approved for patients who failed with androgen deprivation therapy and have developed castration-resistant prostate cancer. More than 80% of these patients develop bone metastases. The binding of enzal...

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Detalles Bibliográficos
Autores principales:	Vander Ark, Alexandra, Cao, Jingchen, Li, Xiaohong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992404/ https://www.ncbi.nlm.nih.gov/pubmed/29911070 http://dx.doi.org/10.3389/fonc.2018.00180

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