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Enhancing Electrotransfection Efficiency through Improvement in Nuclear Entry of Plasmid DNA

The nuclear envelope is a physiological barrier to electrogene transfer. To understand different mechanisms of the nuclear entry for electrotransfected plasmid DNA (pDNA), the current study investigated how manipulation of the mechanisms could affect electrotransfection efficiency (eTE), transgene e...

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Detalles Bibliográficos
Autores principales: Cervia, Lisa D., Chang, Chun-Chi, Wang, Liangli, Mao, Mao, Yuan, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992438/
https://www.ncbi.nlm.nih.gov/pubmed/29858061
http://dx.doi.org/10.1016/j.omtn.2018.02.009