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Enhancing Electrotransfection Efficiency through Improvement in Nuclear Entry of Plasmid DNA
The nuclear envelope is a physiological barrier to electrogene transfer. To understand different mechanisms of the nuclear entry for electrotransfected plasmid DNA (pDNA), the current study investigated how manipulation of the mechanisms could affect electrotransfection efficiency (eTE), transgene e...
Autores principales: | Cervia, Lisa D., Chang, Chun-Chi, Wang, Liangli, Mao, Mao, Yuan, Fan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992438/ https://www.ncbi.nlm.nih.gov/pubmed/29858061 http://dx.doi.org/10.1016/j.omtn.2018.02.009 |
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