De Novo Synthesis of Elastin by Exogenous Delivery of Synthetic Modified mRNA into Skin and Elastin-Deficient Cells

Elastin is one of the most important and abundant extracellular matrix (ECM) proteins that provide elasticity and resilience to tissues and organs, including vascular walls, ligaments, skin, and lung. Besides hereditary diseases, such as Williams-Beuren syndrome (WBS), which results in reduced elast...

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Detalles Bibliográficos
Autores principales: Lescan, Mario, Perl, Regine Mariette, Golombek, Sonia, Pilz, Martin, Hann, Ludmilla, Yasmin, Mahua, Behring, Andreas, Keller, Timea, Nolte, Andrea, Gruhn, Franziska, Kochba, Efrat, Levin, Yotam, Schlensak, Christian, Wendel, Hans Peter, Avci-Adali, Meltem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992474/
https://www.ncbi.nlm.nih.gov/pubmed/29858082
http://dx.doi.org/10.1016/j.omtn.2018.03.013

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