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Tumor xenograft modeling identifies an association between TCF4 loss and breast cancer chemoresistance
Understanding the mechanisms of cancer therapeutic resistance is fundamental to improving cancer care. There is clear benefit from chemotherapy in different breast cancer settings; however, knowledge of the mutations and genes that mediate resistance is incomplete. In this study, by modeling chemore...
Principais autores: | , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Atigo Texto |
Idioma: | English |
Publicado em: |
The Company of Biologists Ltd
2018
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Assuntos: | |
Acesso em linha: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992609/ https://www.ncbi.nlm.nih.gov/pubmed/29666142 http://dx.doi.org/10.1242/dmm.032292 |