Bruno-3 regulates sarcomere component expression and contributes to muscle phenotypes of myotonic dystrophy type 1

Steinert disease, or myotonic dystrophy type 1 (DM1), is a multisystemic disorder caused by toxic noncoding CUG repeat transcripts, leading to altered levels of two RNA binding factors, MBNL1 and CELF1. The contribution of CELF1 to DM1 phenotypes is controversial. Here, we show that the Drosophila C...

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Detalles Bibliográficos
Autores principales: Picchio, Lucie, Legagneux, Vincent, Deschamps, Stephane, Renaud, Yoan, Chauveau, Sabine, Paillard, Luc, Jagla, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992612/
https://www.ncbi.nlm.nih.gov/pubmed/29716962
http://dx.doi.org/10.1242/dmm.031849

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