Bone marrow transplantation corrects haemolytic anaemia in a novel ENU mutagenesis mouse model of TPI deficiency

In this study, we performed a genome-wide N-ethyl-N-nitrosourea (ENU) mutagenesis screen in mice to identify novel genes or alleles that regulate erythropoiesis. Here, we describe a recessive mouse strain, called RBC19, harbouring a point mutation within the housekeeping gene, Tpi1, which encodes th...

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Detalles Bibliográficos
Autores principales: Conway, Ashlee J., Brown, Fiona C., Hortle, Elinor J., Burgio, Gaetan, Foote, Simon J., Morton, Craig J., Jane, Stephen M., Curtis, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992613/
https://www.ncbi.nlm.nih.gov/pubmed/29720471
http://dx.doi.org/10.1242/dmm.034678

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992613/
https://www.ncbi.nlm.nih.gov/pubmed/29720471
http://dx.doi.org/10.1242/dmm.034678

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