Hamartoma-like lesions in the mouse retina: an animal model of Pten hamartoma tumour syndrome

PTEN hamartoma tumour syndrome (PHTS) is a heterogeneous group of rare, autosomal dominant disorders associated with PTEN germline mutations. PHTS patients routinely develop hamartomas, which are benign tissue overgrowths comprised of disorganized ‘normal’ cells. Efforts to generate PHTS animal mode...

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Detalles Bibliográficos
Autores principales: Tachibana, Nobuhiko, Touahri, Yacine, Dixit, Rajiv, David, Luke Ajay, Adnani, Lata, Cantrup, Robert, Aavani, Tooka, Wong, Rachel O., Logan, Cairine, Kurek, Kyle C., Schuurmans, Carol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992614/
https://www.ncbi.nlm.nih.gov/pubmed/29716894
http://dx.doi.org/10.1242/dmm.031005

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