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Ammoxetine attenuates diabetic neuropathic pain through inhibiting microglial activation and neuroinflammation in the spinal cord

BACKGROUND: Diabetic neuropathic pain (DNP) is a common and distressing complication in patients with diabetes, and the underlying mechanism remains unclear. Tricyclic antidepressants (TCAs) and serotonin and norepinephrine reuptake inhibitors (SNRIs) are recommended as first-line drugs for DNP. Amm...

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Detalles Bibliográficos
Autores principales: Zhang, Ting-Ting, Xue, Rui, Fan, Shi-Yong, Fan, Qiong-Yin, An, Lei, Li, Juan, Zhu, Lei, Ran, Yu-Hua, Zhang, Li-Ming, Zhong, Bo-Hua, Li, Yun-Feng, Ye, Cai-Ying, Zhang, You-Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992688/
https://www.ncbi.nlm.nih.gov/pubmed/29879988
http://dx.doi.org/10.1186/s12974-018-1216-3

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