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Optimal size of pterygium excision for limbal conjunctival autograft using fibrin glue in primary pterygia

BACKGROUND: In our study we describe a method that optimizes size of excision and autografting for primary pterygia along with the use of intraoperative MMC and fibrin glue. Our objective is to propose a simple, optimizedpterygium surgical technique with excellent aesthetic outcomes and low rates of...

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Autores principales: Hwang, Ho Sik, Cho, Kyong Jin, Rand, Gabriel, Chuck, Roy S., Kwon, Ji Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992752/
https://www.ncbi.nlm.nih.gov/pubmed/29879926
http://dx.doi.org/10.1186/s12886-018-0790-6
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author Hwang, Ho Sik
Cho, Kyong Jin
Rand, Gabriel
Chuck, Roy S.
Kwon, Ji Won
author_facet Hwang, Ho Sik
Cho, Kyong Jin
Rand, Gabriel
Chuck, Roy S.
Kwon, Ji Won
author_sort Hwang, Ho Sik
collection PubMed
description BACKGROUND: In our study we describe a method that optimizes size of excision and autografting for primary pterygia along with the use of intraoperative MMC and fibrin glue. Our objective is to propose a simple, optimizedpterygium surgical technique with excellent aesthetic outcomes and low rates of recurrence and otheradverse events. METHODS: Retrospective chart review of 78 consecutive patients with stage III primary pterygia who underwent an optimal excision technique by three experienced surgeons. The technique consisted of removal of the pterygium head, excision of the pterygium body and Tenon’s layer limited in proportion to the length of the head, application of intraoperative mitomycin C to the defect, harvest of superior bulbar limbal conjunctival graft, adherence of graft with fibrin glue. Outcomes included operative time, follow up period, pterygium recurrence, occurrences of incorrectly sized grafts, and other complications. RESULTS: All patients were followed up for more than a year. Of the 78 patients, there were 2 cases of pterygium recurrence (2.6%). There was one case of wound dehiscence secondary to small-sized donor conjunctivaand one case of over-sized donor conjunctiva, neither of which required surgical correction. There were no toxic complications associated with the use of mitomycin C. CONCLUSION: Correlating the excision of the pterygium body and underlying Tenon’s layer to the length of the pterygium head, along with the use intraoperative mitomycin C, limbal conjunctival autografting, and fibrin adhesionresulted in excellent outcomes with a low rate of recurrence for primary pterygia.
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spelling pubmed-59927522018-07-05 Optimal size of pterygium excision for limbal conjunctival autograft using fibrin glue in primary pterygia Hwang, Ho Sik Cho, Kyong Jin Rand, Gabriel Chuck, Roy S. Kwon, Ji Won BMC Ophthalmol Research Article BACKGROUND: In our study we describe a method that optimizes size of excision and autografting for primary pterygia along with the use of intraoperative MMC and fibrin glue. Our objective is to propose a simple, optimizedpterygium surgical technique with excellent aesthetic outcomes and low rates of recurrence and otheradverse events. METHODS: Retrospective chart review of 78 consecutive patients with stage III primary pterygia who underwent an optimal excision technique by three experienced surgeons. The technique consisted of removal of the pterygium head, excision of the pterygium body and Tenon’s layer limited in proportion to the length of the head, application of intraoperative mitomycin C to the defect, harvest of superior bulbar limbal conjunctival graft, adherence of graft with fibrin glue. Outcomes included operative time, follow up period, pterygium recurrence, occurrences of incorrectly sized grafts, and other complications. RESULTS: All patients were followed up for more than a year. Of the 78 patients, there were 2 cases of pterygium recurrence (2.6%). There was one case of wound dehiscence secondary to small-sized donor conjunctivaand one case of over-sized donor conjunctiva, neither of which required surgical correction. There were no toxic complications associated with the use of mitomycin C. CONCLUSION: Correlating the excision of the pterygium body and underlying Tenon’s layer to the length of the pterygium head, along with the use intraoperative mitomycin C, limbal conjunctival autografting, and fibrin adhesionresulted in excellent outcomes with a low rate of recurrence for primary pterygia. BioMed Central 2018-06-07 /pmc/articles/PMC5992752/ /pubmed/29879926 http://dx.doi.org/10.1186/s12886-018-0790-6 Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Hwang, Ho Sik
Cho, Kyong Jin
Rand, Gabriel
Chuck, Roy S.
Kwon, Ji Won
Optimal size of pterygium excision for limbal conjunctival autograft using fibrin glue in primary pterygia
title Optimal size of pterygium excision for limbal conjunctival autograft using fibrin glue in primary pterygia
title_full Optimal size of pterygium excision for limbal conjunctival autograft using fibrin glue in primary pterygia
title_fullStr Optimal size of pterygium excision for limbal conjunctival autograft using fibrin glue in primary pterygia
title_full_unstemmed Optimal size of pterygium excision for limbal conjunctival autograft using fibrin glue in primary pterygia
title_short Optimal size of pterygium excision for limbal conjunctival autograft using fibrin glue in primary pterygia
title_sort optimal size of pterygium excision for limbal conjunctival autograft using fibrin glue in primary pterygia
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992752/
https://www.ncbi.nlm.nih.gov/pubmed/29879926
http://dx.doi.org/10.1186/s12886-018-0790-6
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