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p300 promotes proliferation, migration, and invasion via inducing epithelial-mesenchymal transition in non-small cell lung cancer cells

BACKGROUND: Histone acetyltransferase p300 is a crucial transcriptional coactivator and has been implicated as a poor prognostic factor in human cancers. However, little is known about the substantial functions and mechanisms of p300 in NSCLC proliferation and distant metastasis. METHODS: We constru...

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Detalles Bibliográficos
Autores principales: Hou, Xue, Gong, Run, Zhan, Jianhua, Zhou, Ting, Ma, Yuxiang, Zhao, Yuanyuan, Zhang, Yaxiong, Chen, Gang, Zhang, Zhonghan, Ma, Shuxiang, Chen, Xi, Gao, Fangfang, Hong, Shaodong, Luo, Fan, Fang, Wenfeng, Yang, Yunpeng, Huang, Yan, Chen, Likun, Yang, Haoxian, Zhang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992873/
https://www.ncbi.nlm.nih.gov/pubmed/29879950
http://dx.doi.org/10.1186/s12885-018-4559-3