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Basket trial of TRK inhibitors demonstrates efficacy in TRK fusion-positive cancers
Unlike many conventional cancers with preferential patterns of oncogenic genetic alterations, TRK fusions resulting from NTRK1/2/3 genetic alterations drive oncogenic transformations in more than 20 different malignancies over diverse tissue/cell lineages, in both children and adults. A recent “bask...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992878/ https://www.ncbi.nlm.nih.gov/pubmed/29880008 http://dx.doi.org/10.1186/s13045-018-0622-4 |