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Data on specificity of [(18)F]GE180 uptake for TSPO expression in rodent brain and myocardium
Data in this article show radioligand uptake (to gamma counter and positron-emission-tomography) as well as polymerase chain reaction analyses of 18 kDa translocator protein (TSPO) quantification. We confirmed specificity of [(18)F]GE180 binding of rodent brain and myocardium by blocking experiments...
| Autores principales: | , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992977/ https://www.ncbi.nlm.nih.gov/pubmed/29892655 http://dx.doi.org/10.1016/j.dib.2018.04.133 |
| _version_ | 1783330145731346432 |
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| author | Deussing, Maximilian Blume, Tanja Vomacka, Lena Mahler, Christoph Focke, Carola Todica, Andrei Unterrainer, Marcus Albert, Nathalie L. Lindner, Simon von Ungern-Sternberg, Barbara Baumann, Karlheinz Zwergal, Andreas Bartenstein, Peter Herms, Jochen Rominger, Axel Brendel, Matthias |
| author_facet | Deussing, Maximilian Blume, Tanja Vomacka, Lena Mahler, Christoph Focke, Carola Todica, Andrei Unterrainer, Marcus Albert, Nathalie L. Lindner, Simon von Ungern-Sternberg, Barbara Baumann, Karlheinz Zwergal, Andreas Bartenstein, Peter Herms, Jochen Rominger, Axel Brendel, Matthias |
| author_sort | Deussing, Maximilian |
| collection | PubMed |
| description | Data in this article show radioligand uptake (to gamma counter and positron-emission-tomography) as well as polymerase chain reaction analyses of 18 kDa translocator protein (TSPO) quantification. We confirmed specificity of [(18)F]GE180 binding of rodent brain and myocardium by blocking experiments with prior application of non-radioactive GE180, using dynamic in vivo positron-emission-tomography and ex vivo gamma counter measurements. Expression of TSPO was compared between rodent brain and myocardium by quantitative polymerase chain reaction. |
| format | Online Article Text |
| id | pubmed-5992977 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2018 |
| publisher | Elsevier |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-59929772018-06-11 Data on specificity of [(18)F]GE180 uptake for TSPO expression in rodent brain and myocardium Deussing, Maximilian Blume, Tanja Vomacka, Lena Mahler, Christoph Focke, Carola Todica, Andrei Unterrainer, Marcus Albert, Nathalie L. Lindner, Simon von Ungern-Sternberg, Barbara Baumann, Karlheinz Zwergal, Andreas Bartenstein, Peter Herms, Jochen Rominger, Axel Brendel, Matthias Data Brief Neuroscience Data in this article show radioligand uptake (to gamma counter and positron-emission-tomography) as well as polymerase chain reaction analyses of 18 kDa translocator protein (TSPO) quantification. We confirmed specificity of [(18)F]GE180 binding of rodent brain and myocardium by blocking experiments with prior application of non-radioactive GE180, using dynamic in vivo positron-emission-tomography and ex vivo gamma counter measurements. Expression of TSPO was compared between rodent brain and myocardium by quantitative polymerase chain reaction. Elsevier 2018-05-05 /pmc/articles/PMC5992977/ /pubmed/29892655 http://dx.doi.org/10.1016/j.dib.2018.04.133 Text en © 2018 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
| spellingShingle | Neuroscience Deussing, Maximilian Blume, Tanja Vomacka, Lena Mahler, Christoph Focke, Carola Todica, Andrei Unterrainer, Marcus Albert, Nathalie L. Lindner, Simon von Ungern-Sternberg, Barbara Baumann, Karlheinz Zwergal, Andreas Bartenstein, Peter Herms, Jochen Rominger, Axel Brendel, Matthias Data on specificity of [(18)F]GE180 uptake for TSPO expression in rodent brain and myocardium |
| title | Data on specificity of [(18)F]GE180 uptake for TSPO expression in rodent brain and myocardium |
| title_full | Data on specificity of [(18)F]GE180 uptake for TSPO expression in rodent brain and myocardium |
| title_fullStr | Data on specificity of [(18)F]GE180 uptake for TSPO expression in rodent brain and myocardium |
| title_full_unstemmed | Data on specificity of [(18)F]GE180 uptake for TSPO expression in rodent brain and myocardium |
| title_short | Data on specificity of [(18)F]GE180 uptake for TSPO expression in rodent brain and myocardium |
| title_sort | data on specificity of [(18)f]ge180 uptake for tspo expression in rodent brain and myocardium |
| topic | Neuroscience |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992977/ https://www.ncbi.nlm.nih.gov/pubmed/29892655 http://dx.doi.org/10.1016/j.dib.2018.04.133 |
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