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Characterization data for T cell-specific Blimp-1 transgenic C57BL/6 mice

This article is the first to provide characterization data regarding naive C57BL/6 transgenic mice with overexpression of B lymphocyte-induced maturation protein 1 (Blimp-1) under a T cell-specific pLCK promoter. The data presented are related to phenotype, Blimp-1 overexpression levels, T cell deve...

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Detalles Bibliográficos
Autores principales: Wang, Aline Yen Ling, Loh, Charles Yuen Yung, Chen, Shyi-Jou, Kao, Huang-Kai, Lin, Cheng-Hung, Chuang, Sheng-Hao, Lee, Chin-Ming, Sytwu, Huey-Kang, Wei, Fu-Chan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992980/
https://www.ncbi.nlm.nih.gov/pubmed/29892625
http://dx.doi.org/10.1016/j.dib.2018.04.132
Descripción
Sumario:This article is the first to provide characterization data regarding naive C57BL/6 transgenic mice with overexpression of B lymphocyte-induced maturation protein 1 (Blimp-1) under a T cell-specific pLCK promoter. The data presented are related to phenotype, Blimp-1 overexpression levels, T cell development and T cell proliferation for Blimp-1 transgenic mice. For further Blimp-1 overexpressed T cell findings regarding skin allotransplantation, please refer to the research article “Blimp-1 prolongs allograft survival without regimen via influencing T cell development in favor of regulatory T cells while suppressing Th1” (Wang et al., 2018) [1].