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Glutamine synthetase mediates sorafenib sensitivity in β-catenin-active hepatocellular carcinoma cells
The gene encoding β-catenin is frequently mutated in hepatocellular carcinoma cells. While the oncogenicity of β-catenin has been extensively studied, β-catenin’s role in hepatocellular carcinoma tumor metabolism is currently less well understood. In this study, we found that β-catenin regulates the...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992988/ https://www.ncbi.nlm.nih.gov/pubmed/29303508 http://dx.doi.org/10.1038/emm.2017.174 |