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The data of change in macrophage gene expression which induced by perilipin 1 overexpression
The data presented here are related to the research article entitled “Overexpression of Perilipin1 protects against atheroma progression in apolipoprotein E knockout mice” [1]. This paper describes data that were obtained from perilipin 1 (PLIN1) transgenic mice (Plin1Tg) regarding atherosclerosis....
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993010/ https://www.ncbi.nlm.nih.gov/pubmed/29892631 http://dx.doi.org/10.1016/j.dib.2018.05.027 |
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author | Yamamoto, Kohei Miyoshi, Hideaki Cho, Kyu Yong Nakamura, Akinobu Greenberg, Andrew S. Atsumi, Tatsuya |
author_facet | Yamamoto, Kohei Miyoshi, Hideaki Cho, Kyu Yong Nakamura, Akinobu Greenberg, Andrew S. Atsumi, Tatsuya |
author_sort | Yamamoto, Kohei |
collection | PubMed |
description | The data presented here are related to the research article entitled “Overexpression of Perilipin1 protects against atheroma progression in apolipoprotein E knockout mice” [1]. This paper describes data that were obtained from perilipin 1 (PLIN1) transgenic mice (Plin1Tg) regarding atherosclerosis. The main aim of collecting the data was to clarify the role of PLIN1 in the pathophysiology of atherosclerosis. The data were collected from C57BL/6J mice, apolipoprotein E knockout mice (ApoeKO) and Plin1Tg/ApoeKO. The atherosclerotic lesion areas of aorta were 3.3 ± 1.2% in C57BL/6J mice, 14.2 ± 3.2% in ApoeKO, and 5.6 ± 1.9% in Plin1Tg/ApoeKO. Body weight, gonadal adipose mass and plasma triglyceride concentrations were comparable among the three groups [1]. Furthermore, PLIN1 overexpression did not affect the gene expressions related to cholesterol influx and efflux in macrophage. |
format | Online Article Text |
id | pubmed-5993010 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-59930102018-06-11 The data of change in macrophage gene expression which induced by perilipin 1 overexpression Yamamoto, Kohei Miyoshi, Hideaki Cho, Kyu Yong Nakamura, Akinobu Greenberg, Andrew S. Atsumi, Tatsuya Data Brief Medicine and Dentistry The data presented here are related to the research article entitled “Overexpression of Perilipin1 protects against atheroma progression in apolipoprotein E knockout mice” [1]. This paper describes data that were obtained from perilipin 1 (PLIN1) transgenic mice (Plin1Tg) regarding atherosclerosis. The main aim of collecting the data was to clarify the role of PLIN1 in the pathophysiology of atherosclerosis. The data were collected from C57BL/6J mice, apolipoprotein E knockout mice (ApoeKO) and Plin1Tg/ApoeKO. The atherosclerotic lesion areas of aorta were 3.3 ± 1.2% in C57BL/6J mice, 14.2 ± 3.2% in ApoeKO, and 5.6 ± 1.9% in Plin1Tg/ApoeKO. Body weight, gonadal adipose mass and plasma triglyceride concentrations were comparable among the three groups [1]. Furthermore, PLIN1 overexpression did not affect the gene expressions related to cholesterol influx and efflux in macrophage. Elsevier 2018-05-15 /pmc/articles/PMC5993010/ /pubmed/29892631 http://dx.doi.org/10.1016/j.dib.2018.05.027 Text en © 2018 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Medicine and Dentistry Yamamoto, Kohei Miyoshi, Hideaki Cho, Kyu Yong Nakamura, Akinobu Greenberg, Andrew S. Atsumi, Tatsuya The data of change in macrophage gene expression which induced by perilipin 1 overexpression |
title | The data of change in macrophage gene expression which induced by perilipin 1 overexpression |
title_full | The data of change in macrophage gene expression which induced by perilipin 1 overexpression |
title_fullStr | The data of change in macrophage gene expression which induced by perilipin 1 overexpression |
title_full_unstemmed | The data of change in macrophage gene expression which induced by perilipin 1 overexpression |
title_short | The data of change in macrophage gene expression which induced by perilipin 1 overexpression |
title_sort | data of change in macrophage gene expression which induced by perilipin 1 overexpression |
topic | Medicine and Dentistry |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993010/ https://www.ncbi.nlm.nih.gov/pubmed/29892631 http://dx.doi.org/10.1016/j.dib.2018.05.027 |
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