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Shift in VEGFA isoform balance towards more angiogenic variants is associated with tumor stage and differentiation of human hepatocellular carcinoma
BACKGROUND: Hepatocellular carcinoma (HCC) is the most common and aggressive type of malignant liver tumor. HCC progression depends significantly on its vascularization and formation of new blood vessels. Vascular endothelial growth factor A (VEGFA) is a crucial regulator of tumor vascularization an...
Autores principales: | Chesnokov, Mikhail S., Khesina, Polina A., Shavochkina, Darya A., Kustova, Inna F., Dyakov, Leonid M., Morozova, Olga V., Mugue, Nikolai S., Kudashkin, Nikolay E., Moroz, Ekaterina A., Patyutko, Yuri I., Lazarevich, Natalia L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993022/ https://www.ncbi.nlm.nih.gov/pubmed/29888133 http://dx.doi.org/10.7717/peerj.4915 |
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