Cargando…

Shift in VEGFA isoform balance towards more angiogenic variants is associated with tumor stage and differentiation of human hepatocellular carcinoma

BACKGROUND: Hepatocellular carcinoma (HCC) is the most common and aggressive type of malignant liver tumor. HCC progression depends significantly on its vascularization and formation of new blood vessels. Vascular endothelial growth factor A (VEGFA) is a crucial regulator of tumor vascularization an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chesnokov, Mikhail S., Khesina, Polina A., Shavochkina, Darya A., Kustova, Inna F., Dyakov, Leonid M., Morozova, Olga V., Mugue, Nikolai S., Kudashkin, Nikolay E., Moroz, Ekaterina A., Patyutko, Yuri I., Lazarevich, Natalia L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PeerJ Inc. 2018
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993022/ https://www.ncbi.nlm.nih.gov/pubmed/29888133 http://dx.doi.org/10.7717/peerj.4915

Ejemplares similares

VEGFA Isoforms as Pro-Angiogenic Therapeutics for Cerebrovascular Diseases
por: White, Amanda Louise, et al.
Publicado: (2023)

RNA-Sequencing data supports the existence of novel VEGFA splicing events but not of VEGFA(xxx)b isoforms
por: Bridgett, Stephen, et al.
Publicado: (2017)

The balance of proangiogenic and antiangiogenic VEGFA isoforms regulate follicle development
por: McFee, Renee M., et al.
Publicado: (2012)

Retinopathy of prematurity shows alterations in Vegfa(164) isoform expression
por: Mezu-Ndubuisi, Olachi J., et al.
Publicado: (2021)

Uncovering the diversity of endemic Ethiopian fauna: complete mitochondrial genomes of four Lophuromys species (Rodentia, Muridae)
por: Komarova, Valeria A., et al.
Publicado: (2022)

Role of the angiogenic components, VEGFA, FGF2, OPN and RHOC, in urothelial cell carcinoma of the urinary bladder
por: ZARAVINOS, APOSTOLOS, et al.
Publicado: (2012)

Local angiogenic interplay of Vegfc/d and Vegfa controls brain region-specific emergence of fenestrated capillaries
por: Parab, Sweta, et al.
Publicado: (2023)

Aberrant expression of alternative isoforms of transcription factors in hepatocellular carcinoma
por: Krivtsova, Olga, et al.
Publicado: (2018)

Molecular features of interaction between VEGFA and anti-angiogenic drugs used in retinal diseases: a computational approach
por: Platania, Chiara B. M., et al.
Publicado: (2015)

Synergistic Anti-Angiogenic Effects Using Peptide-Based Combinatorial Delivery of siRNAs Targeting VEGFA, VEGFR1, and Endoglin Genes
por: Egorova, Anna A., et al.
Publicado: (2019)

Differences in activation of intracellular signaling in primary human retinal endothelial cells between isoforms of VEGFA 165
por: Dailey, Wendelin, et al.
Publicado: (2021)

Erratum: Molecular features of interaction between VEGFA and anti-angiogenic drugs used in retinal diseases: a computational approach
Publicado: (2016)

Expression of CASC8 RNA in Human Pancreatic Cancer Cell Lines
por: Burenina, O. Y., et al.
Publicado: (2022)

Erratum to: Expression of CASC8 RNA in Human Pancreatic Cancer Cell Lines
por: Burenina, O. Y., et al.
Publicado: (2023)

Urban air pollution by carcinogenic and genotoxic polyaromatic hydrocarbons in the former USSR.
por: Khesina AYa
Publicado: (1994)

Chamaejasmine B Induces the Anergy of Vascular Endothelial Cells to VEGFA Pro-angiogenic Signal by Autophagic Regulation of VEGFR2 in Breast Cancer
por: Li, Qi, et al.
Publicado: (2018)

P660: NEXT-GENERATION SEQUENCING (NGS) FOR DETECTING BCR::ABL-INDEPENDENT MUTATIONS IN PATIENTS WITH CHRONIC MYELOID LEUKEMIA WITH RESISTANCE TO TYROSINE KINASE INHIBITOR TREATMENT
por: Kustova, Daria, et al.
Publicado: (2023)

Vegfa Protects the Glomerular Microvasculature in Diabetes
por: Sivaskandarajah, Gavasker A., et al.
Publicado: (2012)

Cystatin C Expression is Promoted by VEGFA Blocking, With Inhibitory Effects on Endothelial Cell Angiogenic Functions Including Proliferation, Migration, and Chorioallantoic Membrane Angiogenesis
por: Li, Zhenkun, et al.
Publicado: (2018)

Do Anti-Angiogenic VEGF (VEGFxxxb) Isoforms Exist? A Cautionary Tale
por: Harris, Sheila, et al.
Publicado: (2012)

Complete mitochondrial genomes of representatives of two endemic sculpin families (Perciformes: Cottoidei) from Baikal – the world’s largest and deepest lake
por: Mugue, Nikolai, et al.
Publicado: (2021)

VEGFA/VEGFR2-targeted therapies prevent the VEGFA-induced proliferation of regulatory T cells in cancer
por: Terme, Magali, et al.
Publicado: (2013)

Inhibition of VEGFA Increases the Sensitivity of Ovarian Cancer Cells to Chemotherapy by Suppressing VEGFA-Mediated Autophagy
por: Li, Xia, et al.
Publicado: (2020)

Non-equilibrium reacting gas flows: kinetic theory of transport and relaxation processes
por: Nagnibeda, Ekaterina, et al.
Publicado: (2009)

Effect of method of deduplication on estimation of differential gene expression using RNA-seq
por: Klepikova, Anna V., et al.
Publicado: (2017)

VEGF(121)b and VEGF(165)b are weakly angiogenic isoforms of VEGF-A
por: Catena, Raúl, et al.
Publicado: (2010)

An anti-angiogenic isoform of VEGF-A contributes to impaired vascularization in peripheral artery disease
por: Kikuchi, Ryosuke, et al.
Publicado: (2014)

Regulation of Vascular Endothelial Growth Factor (VEGF) Splicing from Pro-angiogenic to Anti-angiogenic Isoforms: A NOVEL THERAPEUTIC STRATEGY FOR ANGIOGENESIS
por: Nowak, Dawid G., et al.
Publicado: (2010)

Complete mitochondrial genomes of the critically endangered Ship sturgeon Acipenser nudiventris from two seas
por: Mugue, Nikolai, et al.
Publicado: (2016)

Architecture of Parallel Adaptation in Ten Lacustrine Threespine Stickleback Populations from the White Sea Area
por: Terekhanova, Nadezhda V, et al.
Publicado: (2019)

Characteristics of the Fecal Microbiome of Piglets with Diarrhea Identified Using Shotgun Metagenomics Sequencing
por: Gryaznova, Mariya, et al.
Publicado: (2023)

Mesenchymal VEGFA induces aberrant differentiation in heterotopic ossification
por: Hwang, Charles, et al.
Publicado: (2019)

GPR4 signaling is essential for the promotion of acid-mediated angiogenic capacity of endothelial progenitor cells by activating STAT3/VEGFA pathway in patients with coronary artery disease
por: Ouyang, Shun, et al.
Publicado: (2021)

Impact of VEGFA polymorphisms on glioma risk in Chinese
por: Zhao, Peng, et al.
Publicado: (2017)

Vegfa Impacts Early Myocardium Development in Zebrafish
por: Zhu, Diqi, et al.
Publicado: (2017)

Autophagy inhibition potentiates the anti-angiogenic property of multikinase inhibitor anlotinib through JAK2/STAT3/VEGFA signaling in non-small cell lung cancer cells
por: Liang, Lijun, et al.
Publicado: (2019)

The endogenous anti-angiogenic VEGF isoform, VEGF(165)b inhibits human tumour growth in mice
por: Rennel, E S, et al.
Publicado: (2008)

VEGFA activates an epigenetic pathway upregulating ovarian cancer‐initiating cells
por: Jang, Kibeom, et al.
Publicado: (2017)

Estrogen receptor 1 (ESR1) regulates VEGFA in adipose tissue
por: Fatima, L. A., et al.
Publicado: (2017)

Whole Exome Sequencing Study Suggests an Impact of FANCA, CDH1 and VEGFA Genes on Diffuse Gastric Cancer Development
por: Nurgalieva, Alfiia, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_3nds9b8ldd4u904pcemd3clve6