Cdc42 Regulates Neuronal Polarity during Cerebellar Axon Formation and Glial-Guided Migration

CNS cortical histogenesis depends on polarity signaling pathways that regulate cell adhesion and motility. Here we report that conditional deletion of the Rho GTPase Cdc42 in cerebellar granule cell precursors (GCPs) results in abnormalities in cerebellar foliation revealed by iDISCO clearing method...

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Detalles Bibliográficos
Autores principales: Govek, Eve-Ellen, Wu, Zhuhao, Acehan, Devrim, Molina, Henrik, Rivera, Keith, Zhu, Xiaodong, Fang, Yin, Tessier-Lavigne, Marc, Hatten, Mary Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993048/
https://www.ncbi.nlm.nih.gov/pubmed/29888765
http://dx.doi.org/10.1016/j.isci.2018.01.004

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