Chromatin Succinylation Correlates with Active Gene Expression and Is Perturbed by Defective TCA Cycle Metabolism

Succinylation is a post-translational protein acylation modification that converts the cationic lysine side chain to an anion with large potential impacts on protein structure and function. Here we characterize the epigenome-wide distribution of succinyllysine marks in chromatin using chromatin immu...

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Detalles Bibliográficos
Autores principales: Smestad, John, Erber, Luke, Chen, Yue, Maher, L. James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993049/
https://www.ncbi.nlm.nih.gov/pubmed/29888767
http://dx.doi.org/10.1016/j.isci.2018.03.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993049/
https://www.ncbi.nlm.nih.gov/pubmed/29888767
http://dx.doi.org/10.1016/j.isci.2018.03.012

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