Xenograft tumors derived from malignant pleural effusion of the patients with non-small-cell lung cancer as models to explore drug resistance

BACKGROUND: Non-small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) mutations or anaplastic lymphoma kinase (ALK) fusions show dramatic responses to specific tyrosine kinase inhibitors (TKIs); however, after 10–12 months, secondary mutations arise that confer resista...

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Detalles Bibliográficos
Autores principales: Xu, Yunhua, Zhang, Feifei, Pan, Xiaoqing, Wang, Guan, Zhu, Lei, Zhang, Jie, Wen, Danyi, Lu, Shun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993147/
https://www.ncbi.nlm.nih.gov/pubmed/29764505
http://dx.doi.org/10.1186/s40880-018-0284-1

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