Cargando…
Peptide inhibitors of the anaphase promoting-complex that cause sensitivity to microtubule poison
There is an interest in identifying Anaphase Promoting-Complex/Cyclosome (APC/C) inhibitors that lead to sensitivity to microtubule poisons as a strategy for targeting cancer cells. Using budding yeast Saccharomyces cerevisiae, peptides derived from the Mitotic Arrest Deficient 2 (Mad2)-binding moti...
Autores principales: | Schuyler, Scott C., Wu, Yueh-Fu Olivia, Chen, Hsin-Yu, Ding, Yi-Shan, Lin, Chia-Jung, Chu, Yu-Ting, Chen, Ting-Chun, Liao, Louis, Tsai, Wei-Wei, Huang, Anna, Wang, Lin-Ing, Liao, Ting-Wei, Jhuo, Jia-Hua, Cheng, Vivien |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993284/ https://www.ncbi.nlm.nih.gov/pubmed/29883473 http://dx.doi.org/10.1371/journal.pone.0198930 |
Ejemplares similares
-
Central-spindle microtubules are strongly coupled to chromosomes during both anaphase A and anaphase B
por: Yu, Che-Hang, et al.
Publicado: (2019) -
Kinetochore microtubule dynamics and the metaphase-anaphase transition
Publicado: (1995) -
Astral microtubules are not required for anaphase B in Saccharomyces cerevisiae
Publicado: (1992) -
Microtubules of the kinetochore fiber turn over in metaphase but not in anaphase
Publicado: (1989) -
Spindle microtubules and their mechanical associations after micromanipulation in anaphase
Publicado: (1982)