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Complex pattern of immune evasion in MSI colorectal cancer

Mismatch repair (MMR)-deficient cancers accumulate multiple insertion/deletion mutations at coding microsatellites (cMS), which give rise to frameshift peptide neoantigens. The high mutational neoantigen load of MMR-deficient cancers is reflected by pronounced anti-tumoral immune responses of the ho...

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Detalles Bibliográficos
Autores principales:	Ozcan, Mine, Janikovits, Jonas, von Knebel Doeberitz, Magnus, Kloor, Matthias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993484/ https://www.ncbi.nlm.nih.gov/pubmed/29900056 http://dx.doi.org/10.1080/2162402X.2018.1445453

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