Increase in PD-L1 expression after pre-operative radiotherapy for soft tissue sarcoma

Soft tissue sarcomas (STS) have minimal expression of PD-L1, a biomarker for PD-1 therapy efficacy. Radiotherapy (RT) has been shown to increase PD-L1 expression pre-clinically. We examined the expression of PD-L1, pre- and post-RT, in 46 Stage II-III STS patients treated with pre-operative RT (50–5...

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Detalles Bibliográficos
Autores principales: Patel, Kirtesh R., Martinez, Anthony, Stahl, John M., Logan, Suzanna J., Perricone, Adam J., Ferris, Matthew J., Buchwald, Zachary S., Chowdhary, Mudit, Delman, Keith A., Monson, David K., Oskouei, Shervin V., Reimer, Nicholas B., Cardona, Kenneth, Edgar, Mark A., Godette, Karen D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993497/
https://www.ncbi.nlm.nih.gov/pubmed/29900051
http://dx.doi.org/10.1080/2162402X.2018.1442168

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