Clonal lineage of high grade serous ovarian cancer in a patient with neurofibromatosis type 1

Neurofibromatosis type 1 (NF1) is caused by mutations in the NF1 gene encoding neurofibromin, which negatively regulates Ras signaling. NF1 patients have an increased risk of developing early onset breast cancer, however, the association between NF1 and high grade serous ovarian cancer (HGSOC) is un...

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Detalles Bibliográficos
Autores principales: Norris, Eric J., Jones, Wendell D., Surleac, Marius D., Petrescu, Andrei J., Destephanis, Darla, Zhang, Qing, Hamadeh, Issam, Kneisl, Jeffrey S., Livasy, Chad A., Ganapathi, Ram N., Tait, David L., Ganapathi, Mahrukh K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993517/
https://www.ncbi.nlm.nih.gov/pubmed/29892687
http://dx.doi.org/10.1016/j.gore.2018.01.005

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