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Tumor molecular profiling of responders and non-responders following pembrolizumab monotherapy in chemotherapy resistant advanced cervical cancer
Optimal treatment for advanced cervical cancer after first line chemotherapy remains undefined. Immune checkpoint inhibition with pembrolizumab, a programmed cell death protein 1(PD-1) inhibitor, is under investigation. We analyzed the micro-environmental and molecular genetic profile of tumors from...
Autores principales: | Ngoi, N.Y.L., Heong, V., Lee, X.W., Huang, Y.Q., Thian, Y.L., Choo, B.A., Lim, D., Lim, Y.W., Lim, S.E., Ilancheran, A., Soong, R., Tan, D.S.P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993533/ https://www.ncbi.nlm.nih.gov/pubmed/29892689 http://dx.doi.org/10.1016/j.gore.2018.01.009 |
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