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Identification and Single-Cell Functional Characterization of an Endodermally Biased Pluripotent Substate in Human Embryonic Stem Cells

Human embryonic stem cells (hESCs) display substantial heterogeneity in gene expression, implying the existence of discrete substates within the stem cell compartment. To determine whether these substates impact fate decisions of hESCs we used a GFP reporter line to investigate the properties of fra...

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Detalles Bibliográficos
Autores principales:	Allison, Thomas F., Smith, Andrew J.H., Anastassiadis, Konstantinos, Sloane-Stanley, Jackie, Biga, Veronica, Stavish, Dylan, Hackland, James, Sabri, Shan, Langerman, Justin, Jones, Mark, Plath, Kathrin, Coca, Daniel, Barbaric, Ivana, Gokhale, Paul, Andrews, Peter W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993559/ https://www.ncbi.nlm.nih.gov/pubmed/29779895 http://dx.doi.org/10.1016/j.stemcr.2018.04.015

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