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Mouse Intestinal Krt15+ Crypt Cells Are Radio-Resistant and Tumor Initiating
Two principal stem cell pools orchestrate the rapid cell turnover in the intestinal epithelium. Rapidly cycling Lgr5+ stem cells are intercalated between the Paneth cells at the crypt base (CBCs) and injury-resistant reserve stem cells reside above the crypt base. The intermediate filament Keratin 1...
Autores principales: | Giroux, Véronique, Stephan, Julien, Chatterji, Priya, Rhoades, Ben, Wileyto, E. Paul, Klein-Szanto, Andres J., Lengner, Christopher J., Hamilton, Kathryn E., Rustgi, Anil K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993649/ https://www.ncbi.nlm.nih.gov/pubmed/29805107 http://dx.doi.org/10.1016/j.stemcr.2018.04.022 |
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