Generation of TCR-Expressing Innate Lymphoid-like Helper Cells that Induce Cytotoxic T Cell-Mediated Anti-leukemic Cell Response

CD4(+) T helper (Th) cell activation is essential for inducing cytotoxic T lymphocyte (CTL) responses against malignancy. We reprogrammed a Th clone specific for chronic myelogenous leukemia (CML)-derived b3a2 peptide to pluripotency and re-differentiated the cells into original TCR-expressing T-lin...

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Detalles Bibliográficos
Autores principales: Ueda, Norihiro, Uemura, Yasushi, Zhang, Rong, Kitayama, Shuichi, Iriguchi, Shoichi, Kawai, Yohei, Yasui, Yutaka, Tatsumi, Minako, Ueda, Tatsuki, Liu, Tian-Yi, Mizoro, Yasutaka, Okada, Chihiro, Watanabe, Akira, Nakanishi, Mahito, Senju, Satoru, Nishimura, Yasuharu, Kuzushima, Kiyotaka, Kiyoi, Hitoshi, Naoe, Tomoki, Kaneko, Shin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993651/
https://www.ncbi.nlm.nih.gov/pubmed/29805109
http://dx.doi.org/10.1016/j.stemcr.2018.04.025

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