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A Pharmacological Rationale to Reduce the Incidence of Opioid Induced Tolerance and Hyperalgesia: A Review
Chronic pain is an important health and social problem. Misuse and abuse of opioids in chronic non-cancer pain management seem to be a huge problem, in some countries. This could probably affect the normal use of such analgesics in patients in need of them. Basic and clinical researches should find...
Autores principales: | Varrassi, Giustino, Fusco, Mariella, Skaper, Stephen D., Battelli, Daniele, Zis, Panagiotis, Coaccioli, Stefano, Pace, Maria Caterina, Paladini, Antonella |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Healthcare
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993687/ https://www.ncbi.nlm.nih.gov/pubmed/29594972 http://dx.doi.org/10.1007/s40122-018-0094-9 |
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