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Impact of physical confinement on nuclei geometry and cell division dynamics in 3D spheroids
Multicellular tumour spheroids are used as a culture model to reproduce the 3D architecture, proliferation gradient and cell interactions of a tumour micro-domain. However, their 3D characterization at the cell scale remains challenging due to size and cell density issues. In this study, we develope...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993719/ https://www.ncbi.nlm.nih.gov/pubmed/29884887 http://dx.doi.org/10.1038/s41598-018-27060-6 |