Cargando…
CREB controls cortical circuit plasticity and functional recovery after stroke
Treatments that stimulate neuronal excitability enhance motor performance after stroke. cAMP-response-element binding protein (CREB) is a transcription factor that plays a key role in neuronal excitability. Increasing the levels of CREB with a viral vector in a small pool of motor neurons enhances m...
Autores principales: | Caracciolo, L., Marosi, M., Mazzitelli, J., Latifi, S., Sano, Y., Galvan, L., Kawaguchi, R., Holley, S., Levine, M. S., Coppola, G., Portera-Cailliau, C., Silva, A. J., Carmichael, S. T. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993731/ https://www.ncbi.nlm.nih.gov/pubmed/29884780 http://dx.doi.org/10.1038/s41467-018-04445-9 |
Ejemplares similares
-
Barrel cortex plasticity after photothrombotic stroke involves potentiating responses of pre-existing circuits but not functional remapping to new circuits
por: Zeiger, William A., et al.
Publicado: (2021) -
Circuit level defects in the developing neocortex of fragile X mice
por: Gonçalves, J. Tiago, et al.
Publicado: (2013) -
Beyond excitation/inhibition imbalance in multidimensional models of neural circuit changes in brain disorders
por: O'Donnell, Cian, et al.
Publicado: (2017) -
The E3 ubiquitin ligase IDOL regulates synaptic ApoER2 levels and is important for plasticity and learning
por: Gao, Jie, et al.
Publicado: (2017) -
Simultaneous 2-photon calcium imaging at different cortical depths in vivo with spatiotemporal multiplexing
por: Cheng, Adrian, et al.
Publicado: (2011)