Cargando…
Kinetics and Fidelity of the Repair of Cas9-Induced Double-Strand DNA Breaks
The RNA-guided DNA endonuclease Cas9 is a powerful tool for genome editing. Little is known about the kinetics and fidelity of the double-strand break (DSB) repair process that follows a Cas9 cutting event in living cells. Here, we developed a strategy to measure the kinetics of DSB repair for singl...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993873/ https://www.ncbi.nlm.nih.gov/pubmed/29804829 http://dx.doi.org/10.1016/j.molcel.2018.04.016 |