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Could low birth weight and preterm birth be associated with significant burden of hip osteoarthritis? A systematic review
BACKGROUND: Approaches for the prevention and treatment of hip osteoarthritis (OA) remain limited. There are recent data suggesting that low birth weight (LBW) and preterm birth may be risk factors for hip osteoarthritis. This has the potential to change the current paradigm of hip osteoarthritis pr...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994049/ https://www.ncbi.nlm.nih.gov/pubmed/29884206 http://dx.doi.org/10.1186/s13075-018-1627-7 |
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author | Hussain, Sultana Monira Ackerman, Ilana N. Wang, Yuanyuan Zomer, Ella Cicuttini, Flavia M. |
author_facet | Hussain, Sultana Monira Ackerman, Ilana N. Wang, Yuanyuan Zomer, Ella Cicuttini, Flavia M. |
author_sort | Hussain, Sultana Monira |
collection | PubMed |
description | BACKGROUND: Approaches for the prevention and treatment of hip osteoarthritis (OA) remain limited. There are recent data suggesting that low birth weight (LBW) and preterm birth may be risk factors for hip osteoarthritis. This has the potential to change the current paradigm of hip osteoarthritis prevention by targeting early life factors. The aim of this review was to examine the available evidence for an association of LBW and preterm birth with hip OA. The potential cost implications associated with total hip arthroplasty were also evaluated. METHODS: Ovid Medline, EMBASE, and Cinahl were searched up until August 2017 using MeSH terms and key words. Methodological quality was evaluated using the National Heart Lung and Blood Institute (NHLBI) quality assessment tool. Qualitative evidence synthesis was performed to summarise the results. Bradford Hill’s criteria for causation including the temporal relationship, consistency, strength of the association, specificity, dose-response relationship, and analogy were used to assess the evidence for causation. Economic modelling was used to calculate the potential economic burden associated with LBW or preterm birth related total hip arthroplasty using Australian data from 2012 to 2015. RESULTS: Five studies, ranging from high to low quality, were included. Hip bone shape abnormalities examined included developmental hip dysplasia and immature hip, and hip osteoarthritis included osteophytes and total hip arthroplasty. A causal link between low birth weight or preterm birth and hip osteoarthritis was found. Of the 30,477 total hip arthroplasties performed for hip osteoarthritis in Australia in 2015, 5791 were estimated to be born preterm and 5273 with low birth weight. This equated to a potential total hip arthroplasty cost of AU$145,136,082 and AU$132,150,222 for these subgroups, respectively. CONCLUSION: Available data suggest that low birth weight and preterm birth are associated with hip bone shape abnormalities and hip osteoarthritis requiring total hip arthroplasty, with a substantial associated financial burden. Given the current lack of effective treatment and prevention strategies for hip osteoarthritis, this offers a new avenue for reducing the future burden of hip osteoarthritis. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13075-018-1627-7) contains supplementary material, which is available to authorized users. |
format | Online Article Text |
id | pubmed-5994049 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-59940492018-07-05 Could low birth weight and preterm birth be associated with significant burden of hip osteoarthritis? A systematic review Hussain, Sultana Monira Ackerman, Ilana N. Wang, Yuanyuan Zomer, Ella Cicuttini, Flavia M. Arthritis Res Ther Review BACKGROUND: Approaches for the prevention and treatment of hip osteoarthritis (OA) remain limited. There are recent data suggesting that low birth weight (LBW) and preterm birth may be risk factors for hip osteoarthritis. This has the potential to change the current paradigm of hip osteoarthritis prevention by targeting early life factors. The aim of this review was to examine the available evidence for an association of LBW and preterm birth with hip OA. The potential cost implications associated with total hip arthroplasty were also evaluated. METHODS: Ovid Medline, EMBASE, and Cinahl were searched up until August 2017 using MeSH terms and key words. Methodological quality was evaluated using the National Heart Lung and Blood Institute (NHLBI) quality assessment tool. Qualitative evidence synthesis was performed to summarise the results. Bradford Hill’s criteria for causation including the temporal relationship, consistency, strength of the association, specificity, dose-response relationship, and analogy were used to assess the evidence for causation. Economic modelling was used to calculate the potential economic burden associated with LBW or preterm birth related total hip arthroplasty using Australian data from 2012 to 2015. RESULTS: Five studies, ranging from high to low quality, were included. Hip bone shape abnormalities examined included developmental hip dysplasia and immature hip, and hip osteoarthritis included osteophytes and total hip arthroplasty. A causal link between low birth weight or preterm birth and hip osteoarthritis was found. Of the 30,477 total hip arthroplasties performed for hip osteoarthritis in Australia in 2015, 5791 were estimated to be born preterm and 5273 with low birth weight. This equated to a potential total hip arthroplasty cost of AU$145,136,082 and AU$132,150,222 for these subgroups, respectively. CONCLUSION: Available data suggest that low birth weight and preterm birth are associated with hip bone shape abnormalities and hip osteoarthritis requiring total hip arthroplasty, with a substantial associated financial burden. Given the current lack of effective treatment and prevention strategies for hip osteoarthritis, this offers a new avenue for reducing the future burden of hip osteoarthritis. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13075-018-1627-7) contains supplementary material, which is available to authorized users. BioMed Central 2018-06-08 2018 /pmc/articles/PMC5994049/ /pubmed/29884206 http://dx.doi.org/10.1186/s13075-018-1627-7 Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Review Hussain, Sultana Monira Ackerman, Ilana N. Wang, Yuanyuan Zomer, Ella Cicuttini, Flavia M. Could low birth weight and preterm birth be associated with significant burden of hip osteoarthritis? A systematic review |
title | Could low birth weight and preterm birth be associated with significant burden of hip osteoarthritis? A systematic review |
title_full | Could low birth weight and preterm birth be associated with significant burden of hip osteoarthritis? A systematic review |
title_fullStr | Could low birth weight and preterm birth be associated with significant burden of hip osteoarthritis? A systematic review |
title_full_unstemmed | Could low birth weight and preterm birth be associated with significant burden of hip osteoarthritis? A systematic review |
title_short | Could low birth weight and preterm birth be associated with significant burden of hip osteoarthritis? A systematic review |
title_sort | could low birth weight and preterm birth be associated with significant burden of hip osteoarthritis? a systematic review |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994049/ https://www.ncbi.nlm.nih.gov/pubmed/29884206 http://dx.doi.org/10.1186/s13075-018-1627-7 |
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