Effect of the 5-HT(4) receptor agonist tegaserod on the expression of GRK2 and GRK6 in the rat gastrointestinal tract

OBJECTIVE: Tegaserod is a 5-hydroxytryptamine type 4 (5-HT(4)) receptor agonist, formerly used in treating constipation predominant irritable bowel syndrome, which desensitizes 5-HT(4) receptors in rat oesophagus and colon in vitro. Desensitization of 5-HT(4) receptors is regulated by G-protein coup...

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Detalles Bibliográficos
Autores principales: Nedi, Teshome, White, Paul J., Coupar, Ian M., Irving, Helen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994065/
https://www.ncbi.nlm.nih.gov/pubmed/29884229
http://dx.doi.org/10.1186/s13104-018-3495-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994065/
https://www.ncbi.nlm.nih.gov/pubmed/29884229
http://dx.doi.org/10.1186/s13104-018-3495-2

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