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Klotho negatively regulated aerobic glycolysis in colorectal cancer via ERK/HIF1α axis

BACKGROUND: Klotho (KL) was originally characterized as an aging suppressor gene, and has been identified as a tumor suppressor gene in a variety of cancers, including colorectal cancer. Recent years have witnessed the importance of metabolism transformation in cancer cell malignancies maintenance....

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Detalles Bibliográficos
Autores principales:	Li, Qingguo, Li, Yaqi, Liang, Lei, Li, Jing, Luo, Dakui, Liu, Qi, Cai, Sanjun, Li, Xinxiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994118/ https://www.ncbi.nlm.nih.gov/pubmed/29884183 http://dx.doi.org/10.1186/s12964-018-0241-2

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