Cargando…

GSK3β Controls mTOR and Prosurvival Signaling in Neurons

Glycogen synthase kinases-3β (GSK3β) is a key regulator of cell homeostasis. In neurons, GSK3β contributes to control of neuronal transmission and plasticity. Despite extensive studies in non-neuronal cells, crosstalk between GSK3β and other signaling pathways remains not well defined in neurons. In...

Descripción completa

Detalles Bibliográficos
Autores principales:	Urbanska, Malgorzata, Gozdz, Agata, Macias, Matylda, Cymerman, Iwona A., Liszewska, Ewa, Kondratiuk, Ilona, Devijver, Herman, Lechat, Benoit, Van Leuven, Fred, Jaworski, Jacek
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994211/ https://www.ncbi.nlm.nih.gov/pubmed/29143288 http://dx.doi.org/10.1007/s12035-017-0823-9

Ejemplares similares

GSK-3β and MMP-9 Cooperate in the Control of Dendritic Spine Morphology
por: Kondratiuk, Ilona, et al.
Publicado: (2016)

Structural Plasticity of Dendritic Spines Requires GSK3α and GSK3β
por: Cymerman, Iwona A., et al.
Publicado: (2015)

GSK3α and GSK3β Phosphorylate Arc and Regulate its Degradation
por: Gozdz, Agata, et al.
Publicado: (2017)

GSK3β activity alleviates epileptogenesis and limits GluA1 phosphorylation
por: Urbanska, Malgorzata, et al.
Publicado: (2018)

Neurological characterization of mice deficient in GSK3α highlight pleiotropic physiological functions in cognition and pathological activity as Tau kinase
por: Maurin, Hervé, et al.
Publicado: (2013)

mTOR controls endoplasmic reticulum–Golgi apparatus trafficking of VSVg in specific cell types
por: Koscielny, Alicja, et al.
Publicado: (2021)

Tauopathy Differentially Affects Cell Adhesion Molecules in Mouse Brain: Early Down-Regulation of Nectin-3 in Stratum Lacunosum Moleculare
por: Maurin, Hervé, et al.
Publicado: (2013)

Adaptor Complex 2 Controls Dendrite Morphology via mTOR-Dependent Expression of GluA2
por: Koscielny, Alicja, et al.
Publicado: (2017)

mTOR kinase is needed for the development and stabilization of dendritic arbors in newly born olfactory bulb neurons
por: Skalecka, Agnieszka, et al.
Publicado: (2016)

GSK3 and Alzheimer’s Disease: Facts and Fiction…
por: Kremer, Anna, et al.
Publicado: (2011)

Spatiotemporal Characterization of mTOR Kinase Activity Following Kainic Acid Induced Status Epilepticus and Analysis of Rat Brain Response to Chronic Rapamycin Treatment
por: Macias, Matylda, et al.
Publicado: (2013)

MicroRNA Expression Profile in TSC Cell Lines and the Impact of mTOR Inhibitor
por: Pawlik, Bartłomiej, et al.
Publicado: (2022)

AAV-Tau Mediates Pyramidal Neurodegeneration by Cell-Cycle Re-Entry without Neurofibrillary Tangle Formation in Wild-Type Mice
por: Jaworski, Tomasz, et al.
Publicado: (2009)

Early Structural and Functional Defects in Synapses and Myelinated Axons in Stratum Lacunosum Moleculare in Two Preclinical Models for Tauopathy
por: Maurin, Hervé, et al.
Publicado: (2014)

mTOR regulates brain morphogenesis by mediating GSK3 signaling
por: Ka, Minhan, et al.
Publicado: (2014)

ESCRT Proteins Control the Dendritic Morphology of Developing and Mature Hippocampal Neurons
por: Firkowska, Marcelina, et al.
Publicado: (2018)

Reactivation of cocaine reward memory engages the Akt/GSK3/mTOR signaling pathway and can be disrupted by GSK3 inhibition
por: Shi, Xiangdang, et al.
Publicado: (2014)

In vitro assessment of antitumor activities of the PI3K/mTOR inhibitor GSK2126458
por: Albawardi, Alia, et al.
Publicado: (2014)

Kainic Acid Induces mTORC1-Dependent Expression of Elmo1 in Hippocampal Neurons
por: Blazejczyk, Magdalena, et al.
Publicado: (2016)

Cytosolic translational responses differ under conditions of severe short-term and long-term mitochondrial stress
por: Samluk, Lukasz, et al.
Publicado: (2019)

Matricellular proteins of the Cyr61/CTGF/NOV (CCN) family and the nervous system
por: Malik, Anna R., et al.
Publicado: (2015)

GSK343 induces autophagy and downregulates the AKT/mTOR signaling pathway in pancreatic cancer cells
por: Xu, Hao, et al.
Publicado: (2019)

Reassessing the role of NAD as a prosurvival factor
por: Preyat, Nicolas, et al.
Publicado: (2015)

Roles of PI3K/AKT/GSK3/mTOR Pathway in Cell Signaling of Mental Illnesses
por: Kitagishi, Yasuko, et al.
Publicado: (2012)

To Live or to Die: Prosurvival Activity of PPARγ in Cancers
por: Wang, Y. Lynn, et al.
Publicado: (2008)

Tuberous sclerosis complex neuropathology requires glutamate-cysteine ligase
por: Malik, Anna R., et al.
Publicado: (2015)

mTOR Pathway and mTOR Inhibitors in Head and Neck Cancer
por: Gao, Wei, et al.
Publicado: (2012)

Dehydrocostuslactone Suppresses Angiogenesis In Vitro and In Vivo through Inhibition of Akt/GSK-3β and mTOR Signaling Pathways
por: Wang, Chih-Ya, et al.
Publicado: (2012)

Myelination and mTOR
por: Figlia, Gianluca, et al.
Publicado: (2017)

Molecular mechanisms of induced pluripotency
por: Kulcenty, Katarzyna, et al.
Publicado: (2015)

mTOR signaling pathway and mTOR inhibitors in cancer: progress and challenges
por: Zou, Zhilin, et al.
Publicado: (2020)

Modeling of Tau-Mediated Synaptic and Neuronal Degeneration in Alzheimer's Disease
por: Jaworski, Tomasz, et al.
Publicado: (2010)

Number 2 Feibi Recipe Ameliorates Pulmonary Fibrosis by Inducing Autophagy Through the GSK-3β/mTOR Pathway
por: Liu, Haoge, et al.
Publicado: (2022)

mTOR Signaling in Cancer and mTOR Inhibitors in Solid Tumor Targeting Therapy
por: Tian, Tian, et al.
Publicado: (2019)

Regulation of Osteoclast Growth and Fusion by mTOR/raptor and mTOR/rictor/Akt
por: Tiedemann, Kerstin, et al.
Publicado: (2017)

Escaping mTOR inhibition for cancer therapy: Tumor suppressor functions of mTOR
por: Villar, Victor H., et al.
Publicado: (2017)

Overcoming mTOR Resistance Mutations with a New Generation mTOR Inhibitor
por: Rodrik-Outmezguine, Vanessa S., et al.
Publicado: (2016)

LMO3 promotes gastric cancer cell invasion and proliferation through Akt-mTOR and Akt-GSK3β signaling
por: Qiu, Yan-Song, et al.
Publicado: (2018)

Suxiao Jiuxin Pill alleviates myocardial ischemia–reperfusion injury through the ALKBH5/GSK3β/mTOR pathway
por: Li, Yiping, et al.
Publicado: (2023)

The prosurvival protein BAG3: a new participant in vascular homeostasis
por: Carrizzo, Albino, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_p5q2qlue3isd6b5vgntcbm1u1v