Cargando…

Next-Generation of Allergen-Specific Immunotherapies: Molecular Approaches

PURPOSE OF REVIEW: The aim of this article is to discuss how allergen-specific immunotherapy (AIT) can be improved through molecular approaches. We provide a summary of next-generation molecular AIT approaches and of their clinical evaluation. Furthermore, we discuss the potential of next generation...

Descripción completa

Detalles Bibliográficos
Autores principales:	Curin, Mirela, Khaitov, Musa, Karaulov, Alexander, Namazova-Baranova, Leyla, Campana, Raffaela, Garib, Victoria, Valenta, Rudolf
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2018
Materias:	Immunotherapy and Immunomodulators (B Vickery, Section Editor)
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994214/ https://www.ncbi.nlm.nih.gov/pubmed/29886521 http://dx.doi.org/10.1007/s11882-018-0790-x

Ejemplares similares

The Cloning and Expression of Human Monoclonal Antibodies: Implications for Allergen Immunotherapy
por: James, Louisa K.
Publicado: (2016)

GRADE-ing the Benefit/Risk Equation in Food Immunotherapy
por: Duca, Bettina, et al.
Publicado: (2019)

The Role of T Helper Type 2 (Th2) Cytokines in the Pathogenesis of Eosinophilic Granulomatosis with Polyangiitis (eGPA): an Illustrative Case and Discussion
por: Milne, Megan E., et al.
Publicado: (2022)

Recombinant allergens for immunotherapy: state of the art
por: Zhernov, Yury, et al.
Publicado: (2019)

Allergen Extracts for In Vivo Diagnosis and Treatment of Allergy: Is There a Future?
por: Valenta, Rudolf, et al.
Publicado: (2018)

The site of allergen expression in hematopoietic cells determines the degree and quality of tolerance induced through molecular chimerism
por: Baranyi, Ulrike, et al.
Publicado: (2013)

Preventive Allergen-Specific Vaccination Against Allergy: Mission Possible?
por: Tulaeva, Inna, et al.
Publicado: (2020)

Single recombinant and purified major allergens and peptides How they are made and how they change allergy diagnosis and treatment
por: Curin, Mirela, et al.
Publicado: (2017)

Allergen Peptides, Recombinant Allergens and Hypoallergens for Allergen-Specific Immunotherapy
por: Marth, Katharina, et al.
Publicado: (2014)

Monitoring Allergen Immunotherapy Effects by Microarray
por: Lupinek, Christian, et al.
Publicado: (2016)

Determination of IgE and IgG reactivity to more than 170 allergen molecules in paper-dried blood spots
por: Garib, Victoria, et al.
Publicado: (2018)

The Molecular Allergen Recognition Profile in China as Basis for Allergen-Specific Immunotherapy
por: D’souza, Nishelle, et al.
Publicado: (2021)

Regulatory T cells inhibit Fas ligand-induced innate and adaptive tumour immunity
por: Simon, Anna Katharina, et al.
Publicado: (2007)

Regulatory T cells can prevent memory CD8(+) T-cell-mediated rejection following polymorphonuclear cell depletion
por: Jones, Nick D, et al.
Publicado: (2010)

Absence of Rac1 and Rac3 GTPases in the nervous system hinders thymic, splenic and immune-competence development
por: Basso, Veronica, et al.
Publicado: (2011)

Induction of transplantation tolerance converts potential effector T cells into graft-protective regulatory T cells
por: Francis, Ross S, et al.
Publicado: (2011)

Killing of myeloid APCs via HLA class I, CD2 and CD226 defines a novel mechanism of suppression by human Tr1 cells
por: Magnani, Chiara F, et al.
Publicado: (2011)

HIV-1 impairs in vitro priming of naïve T cells and gives rise to contact-dependent suppressor T cells
por: Che, Karlhans F, et al.
Publicado: (2010)

Exogenous IFN-γ ex vivo shapes the alloreactive T-cell repertoire by inhibition of Th17 responses and generation of functional Foxp3(+) regulatory T cells
por: Feng, Gang, et al.
Publicado: (2008)

Anti-CD4-mediated selection of Treg in vitro – in vitro suppression does not predict in vivo capacity to prevent graft rejection
por: Oliveira, Vanessa, et al.
Publicado: (2008)

Human β-defensin 3 has immunosuppressive activity in vitro and in vivo
por: Semple, Fiona, et al.
Publicado: (2010)

Enhanced immunogenicity of CTL antigens through mutation of the CD8 binding MHC class I invariant region
por: Wooldridge, Linda, et al.
Publicado: (2007)

A homodimeric complex of HLA-G on normal trophoblast cells modulates antigen-presenting cells via LILRB1
por: Apps, Richard, et al.
Publicado: (2007)

Granulocyte-colony stimulating factor drives the in vitro differentiation of human dendritic cells that induce anergy in naïve T cells
por: Rossetti, Maura, et al.
Publicado: (2010)

Arginine depletion as a mechanism for the immune privilege of corneal allografts
por: Fu, Hongmei, et al.
Publicado: (2011)

Dendritic cell modification as a route to inhibiting corneal graft rejection by the indirect pathway of allorecognition
por: Khan, Adnan, et al.
Publicado: (2013)

PD-1 modulates steady-state and infection-induced IL-10 production in vivo
por: McBerry, Cortez, et al.
Publicado: (2014)

Exacerbated experimental arthritis in Wiskott–Aldrich syndrome protein deficiency: Modulatory role of regulatory B cells
por: Bouma, Gerben, et al.
Publicado: (2014)

Human β-defensin 3 affects the activity of pro-inflammatory pathways associated with MyD88 and TRIF
por: Semple, Fiona, et al.
Publicado: (2011)

IL-33 attenuates the development of experimental autoimmune uveitis
por: Barbour, Mark, et al.
Publicado: (2014)

Glycogen synthase kinase-3 controls IL-10 expression in CD4(+) effector T-cell subsets through epigenetic modification of the IL-10 promoter
por: Hill, Elaine V, et al.
Publicado: (2015)

IL‐12/15/18‐preactivated NK cells suppress GvHD in a mouse model of mismatched hematopoietic cell transplantation
por: Hüber, Christian M., et al.
Publicado: (2015)

OX40 controls effector CD4(+) T-cell expansion, not follicular T helper cell generation in acute Listeria infection
por: Marriott, Clare L, et al.
Publicado: (2014)

Progesterone promotes maternal–fetal tolerance by reducing human maternal T‐cell polyfunctionality and inducing a specific cytokine profile
por: Lissauer, David, et al.
Publicado: (2015)

HLA class I downregulation is associated with enhanced NK‐cell killing of melanoma cells with acquired drug resistance to BRAF inhibitors
por: Sottile, Rosa, et al.
Publicado: (2015)

Exposure to inflammatory cytokines selectively limits GM-CSF production by induced T regulatory cells
por: Reynolds, Ben C, et al.
Publicado: (2014)

Signal regulatory protein alpha (SIRPα) regulates the homeostasis of CD103(+)CD11b(+) DCs in the intestinal lamina propria
por: Scott, Charlotte L, et al.
Publicado: (2014)

Interleukin 17 inhibits progenitor cells in rheumatoid arthritis cartilage
por: Schminke, Boris, et al.
Publicado: (2015)

IL‐12 and IL‐4 activate a CD39‐dependent intrinsic peripheral tolerance mechanism in CD8(+) T cells
por: Noble, Alistair, et al.
Publicado: (2016)

NFATc1 deficiency in T cells protects mice from experimental autoimmune encephalomyelitis
por: Reppert, Sarah, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_0lcjhhai3jdkr448in1hhh771j