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Physical Exercise Modulates L-DOPA-Regulated Molecular Pathways in the MPTP Mouse Model of Parkinson’s Disease
Parkinson’s disease (PD) is characterized by the degeneration of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNpc), resulting in motor and non-motor dysfunction. Physical exercise improves these symptoms in PD patients. To explore the molecular mechanisms underlying the benefici...
Autores principales: | Klemann, Cornelius J. H. M., Xicoy, Helena, Poelmans, Geert, Bloem, Bas R., Martens, Gerard J. M., Visser, Jasper E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994219/ https://www.ncbi.nlm.nih.gov/pubmed/29019056 http://dx.doi.org/10.1007/s12035-017-0775-0 |
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