Aggf1 attenuates neuroinflammation and BBB disruption via PI3K/Akt/NF-κB pathway after subarachnoid hemorrhage in rats

BACKGROUND: Neuroinflammation and blood-brain barrier (BBB) disruption are two critical mechanisms of subarachnoid hemorrhage (SAH)-induced brain injury, which are closely related to patient prognosis. Recently, angiogenic factor with G-patch and FHA domain 1 (Aggf1) was shown to inhibit inflammator...

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Detalles Bibliográficos
Autores principales: Zhu, Qiquan, Enkhjargal, Budbazar, Huang, Lei, Zhang, Tongyu, Sun, Chengmei, Xie, Zhiyi, Wu, Pei, Mo, Jun, Tang, Jiping, Xie, Zongyi, Zhang, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994242/
https://www.ncbi.nlm.nih.gov/pubmed/29885663
http://dx.doi.org/10.1186/s12974-018-1211-8

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