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Effect of lipid and cellulose based matrix former on the release of highly soluble drug from extruded/spheronized, sintered and compacted pellets

BACKGROUND: The study was to develop an extended release (ER) encapsulated and compacted pellets of Atenolol using hydrophobic (wax based and polymeric based) and high viscosity grade hydrophilic matrix formers to control the release of this highly water soluble drug by extrusion/spheronization (ES)...

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Detalles Bibliográficos
Autores principales:	Maboos, Madiha, Yousuf, Rabia Ismail, Shoaib, Muhammad Harris, Nasiri, Iqbal, Hussain, Tazeen, Ahmed, Hafiza Fouzia, Iffat, Wajiha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994249/ https://www.ncbi.nlm.nih.gov/pubmed/29885655 http://dx.doi.org/10.1186/s12944-018-0783-8

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