HSP60 critically regulates endogenous IL-1β production in activated microglia by stimulating NLRP3 inflammasome pathway

BACKGROUND: Interleukin-1β (IL-1β) is one of the most important cytokine secreted by activated microglia as it orchestrates the vicious cycle of inflammation by inducing the expression of various other pro-inflammatory cytokines along with its own production. Microglia-mediated IL-1β production is a...

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Detalles Bibliográficos
Autores principales: Swaroop, Shalini, Mahadevan, Anita, Shankar, Susarla Krishna, Adlakha, Yogita K., Basu, Anirban
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994257/
https://www.ncbi.nlm.nih.gov/pubmed/29885667
http://dx.doi.org/10.1186/s12974-018-1214-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994257/
https://www.ncbi.nlm.nih.gov/pubmed/29885667
http://dx.doi.org/10.1186/s12974-018-1214-5

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