Virulence Associated Gene 8 of Bordetella pertussis Enhances Contact System Activity by Inhibiting the Regulatory Function of Complement Regulator C1 Inhibitor

Bordetella pertussis is a Gram-negative bacterium and the causative agent of whooping cough. Whooping cough is currently re-emerging worldwide and, therefore, still poses a continuous global health threat. B. pertussis expresses several virulence factors that play a role in evading the human immune...

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Detalles Bibliográficos
Autores principales: Hovingh, Elise S., de Maat, Steven, Cloherty, Alexandra P. M., Johnson, Steven, Pinelli, Elena, Maas, Coen, Jongerius, Ilse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994690/
https://www.ncbi.nlm.nih.gov/pubmed/29915576
http://dx.doi.org/10.3389/fimmu.2018.01172

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