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Immunoglobulin G Fragment Crystallizable Glycosylation After Hematopoietic Stem Cell Transplantation Is Dissimilar to Donor Profiles
Immunoglobulin G (IgG) fragment crystallizable (Fc) N-glycosylation has a large influence on the affinity of the antibody for binding to Fcγ-receptors (FcγRs) and C1q protein, thereby influencing immune effector functions. IgG Fc glycosylation is known to be partly regulated by genetics and partly b...
Autores principales: | de Haan, Noortje, van Tol, Maarten J. D., Driessen, Gertjan J., Wuhrer, Manfred, Lankester, Arjan C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994695/ https://www.ncbi.nlm.nih.gov/pubmed/29915589 http://dx.doi.org/10.3389/fimmu.2018.01238 |
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