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Increasing antigen presentation on HSV-1-infected cells increases lesion size but does not alter neural infection or latency

CD8(+) T cells have a role in the control of acute herpes simplex virus (HSV) infection and may also be important in the maintenance of latency. In this study we have explored the consequences of boosting the efficacy of CD8(+) T cells against HSV by increasing the amount of an MHC I-presented epito...

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Detalles Bibliográficos
Autores principales: Russell, Tiffany A., Velusamy, Thilaga, Tseng, Yeu-Yang, Tscharke, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994700/
https://www.ncbi.nlm.nih.gov/pubmed/29620508
http://dx.doi.org/10.1099/jgv.0.001059