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Septic cutaneous emboli revealing a severe case of Klebsiella pneumoniae liver abscess syndrome

INTRODUCTION: Klebsiella pneumoniae liver abscess syndrome (KLAS) is characterized by bacteraemia, liver abscesses and metastatic infection caused by a hypervirulent strain of Klebsiella pneumoniae, usually belonging to the capsular serotype K1 or K2. Initially, KLAS was described in Eastern Asia; r...

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Detalles Bibliográficos
Autores principales: Paraschiv, Florentina, Popescu, Gabriel Adrian, Borcan, Alina Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994707/
https://www.ncbi.nlm.nih.gov/pubmed/29896408
http://dx.doi.org/10.1099/jmmcr.0.005148
Descripción
Sumario:INTRODUCTION: Klebsiella pneumoniae liver abscess syndrome (KLAS) is characterized by bacteraemia, liver abscesses and metastatic infection caused by a hypervirulent strain of Klebsiella pneumoniae, usually belonging to the capsular serotype K1 or K2. Initially, KLAS was described in Eastern Asia; recently isolated cases have been reported from different parts of the world. CASE PRESENTATION: We describe the case of a woman with KLAS including meningeal, ocular and cutaneous metastatic infection and organ dysfunctions (coagulation abnormalities, thrombocytopenia and increased creatinine level). The identification of a hypermucoviscous strain of Klebsiella pneumoniae was possible by culture from one of the cutaneous emboli and subsequently confirmed by blood cultures. The patient fully recovered after abscess drainage and prolonged antibiotic treatment. CONCLUSION: We have pointed out about the importance of sampling each septic focus in order to identify the aetiology of a disseminate infection.