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Septic cutaneous emboli revealing a severe case of Klebsiella pneumoniae liver abscess syndrome

INTRODUCTION: Klebsiella pneumoniae liver abscess syndrome (KLAS) is characterized by bacteraemia, liver abscesses and metastatic infection caused by a hypervirulent strain of Klebsiella pneumoniae, usually belonging to the capsular serotype K1 or K2. Initially, KLAS was described in Eastern Asia; r...

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Autores principales: Paraschiv, Florentina, Popescu, Gabriel Adrian, Borcan, Alina Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994707/
https://www.ncbi.nlm.nih.gov/pubmed/29896408
http://dx.doi.org/10.1099/jmmcr.0.005148
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author Paraschiv, Florentina
Popescu, Gabriel Adrian
Borcan, Alina Maria
author_facet Paraschiv, Florentina
Popescu, Gabriel Adrian
Borcan, Alina Maria
author_sort Paraschiv, Florentina
collection PubMed
description INTRODUCTION: Klebsiella pneumoniae liver abscess syndrome (KLAS) is characterized by bacteraemia, liver abscesses and metastatic infection caused by a hypervirulent strain of Klebsiella pneumoniae, usually belonging to the capsular serotype K1 or K2. Initially, KLAS was described in Eastern Asia; recently isolated cases have been reported from different parts of the world. CASE PRESENTATION: We describe the case of a woman with KLAS including meningeal, ocular and cutaneous metastatic infection and organ dysfunctions (coagulation abnormalities, thrombocytopenia and increased creatinine level). The identification of a hypermucoviscous strain of Klebsiella pneumoniae was possible by culture from one of the cutaneous emboli and subsequently confirmed by blood cultures. The patient fully recovered after abscess drainage and prolonged antibiotic treatment. CONCLUSION: We have pointed out about the importance of sampling each septic focus in order to identify the aetiology of a disseminate infection.
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spelling pubmed-59947072018-06-12 Septic cutaneous emboli revealing a severe case of Klebsiella pneumoniae liver abscess syndrome Paraschiv, Florentina Popescu, Gabriel Adrian Borcan, Alina Maria JMM Case Rep Case Report INTRODUCTION: Klebsiella pneumoniae liver abscess syndrome (KLAS) is characterized by bacteraemia, liver abscesses and metastatic infection caused by a hypervirulent strain of Klebsiella pneumoniae, usually belonging to the capsular serotype K1 or K2. Initially, KLAS was described in Eastern Asia; recently isolated cases have been reported from different parts of the world. CASE PRESENTATION: We describe the case of a woman with KLAS including meningeal, ocular and cutaneous metastatic infection and organ dysfunctions (coagulation abnormalities, thrombocytopenia and increased creatinine level). The identification of a hypermucoviscous strain of Klebsiella pneumoniae was possible by culture from one of the cutaneous emboli and subsequently confirmed by blood cultures. The patient fully recovered after abscess drainage and prolonged antibiotic treatment. CONCLUSION: We have pointed out about the importance of sampling each septic focus in order to identify the aetiology of a disseminate infection. Microbiology Society 2018-04-12 /pmc/articles/PMC5994707/ /pubmed/29896408 http://dx.doi.org/10.1099/jmmcr.0.005148 Text en © 2018 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
spellingShingle Case Report
Paraschiv, Florentina
Popescu, Gabriel Adrian
Borcan, Alina Maria
Septic cutaneous emboli revealing a severe case of Klebsiella pneumoniae liver abscess syndrome
title Septic cutaneous emboli revealing a severe case of Klebsiella pneumoniae liver abscess syndrome
title_full Septic cutaneous emboli revealing a severe case of Klebsiella pneumoniae liver abscess syndrome
title_fullStr Septic cutaneous emboli revealing a severe case of Klebsiella pneumoniae liver abscess syndrome
title_full_unstemmed Septic cutaneous emboli revealing a severe case of Klebsiella pneumoniae liver abscess syndrome
title_short Septic cutaneous emboli revealing a severe case of Klebsiella pneumoniae liver abscess syndrome
title_sort septic cutaneous emboli revealing a severe case of klebsiella pneumoniae liver abscess syndrome
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994707/
https://www.ncbi.nlm.nih.gov/pubmed/29896408
http://dx.doi.org/10.1099/jmmcr.0.005148
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